| Объем | 100 мкл |
| Синонимы | CD32, FCG2, FCG2B,, LY-17, CDW32 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P31994 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.<br/><br/>Stuart S.G., EMBO J. 8:3657-3666(1989).<br />Brooks D.G., J. Exp. Med. 170:1369-1385(1989).<br />Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr292 |
| Области исследований | Immunology,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells treated with PMA using CD32 (Phospho-Tyr292) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-FCGR2B (Tyr292) Antibody.