| Объем | 100 мкл |
| Синонимы | p59-HCK/p60-HCK, Hemopoietic cell kinas, Tyrosine-protein kinase HCK, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P08631 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 521(E-S-Q(p)-Y-Q) derived from Human HCK . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.<br/><br/>Quintrell N., Mol. Cell. Biol. 7:2267-2275(1987) [PubMed: 3496523].<br />Ziegler S.F.,Mol. Cell. Biol. 7:2276-2285(1987) [PubMed: 3453117].<br />Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr521 |
| Области исследований | Immunology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JurKat cells using HCK (Phospho-Tyr522) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-HCK (Tyr521) Antibody.