Объем | 100 мкл |
Синонимы | IBP-3, IBP3, IGF-binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P17936 |
Иммуноген | Peptide sequence around phosphorylation site of serine 183(K-D-S(p)-Q-R) derived from Human IGFBP-3 . |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | <p>IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.<br/><br/>Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 .</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser183 |
Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) antibody.The lane on the right is treated with the antigen-specific peptide.
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