Phospho-ITCH (Tyr420) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | AIF4, AIP4, NAPP1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q96J02 | Иммуноген | Peptide sequence around phosphorylation site of tyrosine 420(F-I-Y(p)-G-N) derived from Human ITCH . | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC,IHC:1:50-1:100 | Примечание | <p>Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.<br/><br/>Chen X., Genomics 73:238-241(2001).<br />Deloukas P., Nature 414:865-871(2001).<br />Wood J.D., Mol. Cell. Neurosci. 11:149-160(1998).<br /></p> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | Абревеатура | Phospho-Tyr420 | Области исследований | Cell biology | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using ITCH (Phospho-Tyr420) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкл | Кат. номер: | CSB-PA180347 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Phospho-ITCH (Tyr420) Antibody. Примечание: дополнительная информация (на английском языке). |
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