Phospho-PTPN11 (Tyr580) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q06124 | | Иммуноген | Peptide sequence around phosphorylation site of tyrosine 580 (R-V-Y(p)-E-N) derived from Human SHP-2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 | | Примечание | <p>Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. <br /><br />Ferjoux G, et al. (2003) Mol Biol Cell. 2003 , 14(9): 3911-3928. <br />Shi ZQ, et al. (2000) Mol Cell Biol , 20(5): 1526-1536. <br />Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A , 96(17): 9677-9682 <br />Manes S, et al. (1999) Mol Cell Biol , 19(4): 3125-3135. <br />Oh ES, et al. (1999) Mol Cell Biol, 19(4): 3205-3215. <br /> ,</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr580 | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2(Phospho-Tyr580) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 | Western blot analysis of extracts from 293 cells, treated with starve or calf intestinal phosphatase (CIP), using SHP-2 (Phospho-Tyr580) Antibody.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA240115 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-PTPN11 (Tyr580) Antibody.
Примечание: дополнительная информация (на английском языке). |
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