| Объем | 100 мкл |
| Синонимы | PAXI, PXN, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P49023 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 118 (H-V-Y(p)-S-F) derived from Human Paxillin. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).<br/><br/>Tao WA, et al.(2005)Nat Methods.2(8): 591-598.<br/>Zhang Y, et al.(2005) Mol Cell Proteomics.4(9): 1240-1250.<br/>Sanders MA, et al.(2005)J Biol Chem.280(25): 23516-23522.<br/>Rush J, et al.(2004) Nat Biotechnol. 23(1): 94-101. <br/><br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr118 |
| Области исследований | Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 3T3 cells untreated or treated with serum using Paxillin(Phospho-Tyr118) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Paxillin(Phospho-Tyr118) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Phospho-PXN (Tyr118) Antibody.