| Объем | 100 мкл |
| Синонимы | KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, polypeptide 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P23443 |
| Иммуноген | Peptide sequence around phosphorylation site of threonine389/412(G-F-T(p)-Y-V) derived from Human p70 S6 Kinase . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.<br/><br/>Hong S, et al. (2014) J Biol Chem<br />Puustinen P, et al. (2014) CJ Cell Biol 204, 713-27 <br />Martineau Y, et al. (2014) Mol Cell Biol 34, 1046-53</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Thr389/412 |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells treated with Insulin using Phospho-p70 S6 Kinase (Thr389/412) antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-RPS6KB1 (Thr389/412) Antibody.