Объем | 100 мкл |
Синонимы | MGF, MPF, Mammary gland factor, STA5A,, STAT5 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P42229 |
Иммуноген | Peptide sequence around phosphorylation site of serine 780 (R-L-S(p)-P-P) derived from Human STAT5A. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
Примечание | Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.<br/><br/>Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.<br/>Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.<br/>Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser780 |
Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells untreated or treated with IL-4 using STAT5A(Phospho-Ser780) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5A(Phospho-Ser780) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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