| Объем | 100 мкл |
| Синонимы | IL-4-STAT, STAT6B, STAT6C |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P42226 |
| Иммуноген | Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | <p>Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. <br /><br />Nelms K, et al. (1999) Annu Rev Immunol. 17:701-738. <br />Malabarba M G, et al. (1996) Biochem. J. 319:865-872. <br />Hou J, et al. (1994) Science. 265:1701-1706. <br />Quelle F W, et al. (1995) Mol Cell Biol. 15: 3336-3343. <br />Takeda K, et al. (1996) Nature. 380: 627-630.</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Thr645 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT6(Phospho-Thr645) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Western blot analysis of extracts from Hela cells, treated with IL-4 or calf intestinal phosphatase (CIP), using STAT6 (Phospho-Thr645) Antibody.
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Наименование: Phospho-STAT6 (Thr645) Antibody.