| Объем | 100 мкл |
| Синонимы | FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8WU20 |
| Иммуноген | Synthesized non-phosphopeptide derived from human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.<br/><br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Xu H., J. Biol. Chem. 273:17987-17990(1998).<br/>Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using FRS2 (Ab-196) antibody.
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Western blot analysis of extracts from 293 cells (Lane 2), using FRS2 (Ab-196) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: FRS2 (Ab-196) Antibody.