PRKAG1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P54619 | Иммуноген | Synthetic peptide of human PRKAG1 | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | Примечание | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Gel: 8%SDS-PAGE,Lysate: 40 ?g,,Primary antibody: CSB-PA614186(PRKAG1 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
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