Объем | 100 мкл |
Синонимы | 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit p44.5, 26S proteasome regulatory subunit S9, PSD11, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O00231 |
Иммуноген | Synthesized peptide derived from internal of human PSMD11. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.<br/><br/>Hoffman L., FEBS Lett. 404:179-184(1997).<br/>Saito A., Gene 203:241-250(1997).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells and HepG2 cells, using PSMD11 antibody.
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