Объем | 50 мкг |
Синонимы | Pertussis toxin subunit 1 (PTX S1) (Islet-activating protein S1) (IAP S1) (NAD-dependent ADP-ribosyltransferase) (EC 2.4.2.-), ptxA |
Клональность | Polyclonal Antibody |
Организм | Bordetella pertussis |
uniprot | P04977 |
Иммуноген | Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA) |
Источник | Rabbit |
Видовая специфичность | Bordetella pertussis |
Применение | ELISA, WB, Recommended dilution: WB:1:1000-1:5000 |
Примечание | S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Bordella pertussis pertussis toxin subunit 1 antibody at 2µg/ml + recombinant Bordella pertussis pertussis toxin subunit 1 100ng
Secondary
Goat polyclonal to rabbit IgG at 1/1000 dilution
Predicted band size: 36 kDa
Observed band size: 36 kDa
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