| Объем | 50 мкг |
| Code NO# | 6A1C2 |
| Синонимы | Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222 |
| Тип антител | Monoclonal Antibody |
| Видовая специфичность | Human |
| Uniport ID | P02753 |
| Иммуноген | Recombinant Human Retinol-binding protein 4 protein |
| Источник | mouse |
| Видовая специфичность 1 | Human,Mouse |
| Перекрестная реактивность | specific for native and denatured forms |
| Применение | ELISA,WB,IHC,Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500 |
| Примечание | Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity. |
| Изотип | IgG1 |
| Метод очистки | >95%,Protein G purified |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Станица на сайте производителя | ссылка |
All lanes: Mouse anti- human Retinol-binding protein 4 monoclonal antibody at 0.3ug/ml
Lane 1: Human positive serum1:10
Lane 2: Human positive serum1:100
Secondary:HRP labeled Goat polyclonal to Mouse IgG at 1/3000 dilution
Predicted band size : 23kd
Observed band size : 27kd
 |
All lanes: Mouse anti- human Retinol-binding protein 4 monoclonal antibody at 0.3ug/ml
Lane 1:RBP4 transfected E.coli lysate
Lane 2:Human positive serum1:100
Lane 3:mouse liver tissue
Secondary:HRP labeled Goat polyclonal to Mouse IgG at 1/3000 dilution
Predicted band size : 23kd
Observed band size : 27kd
 |
Immunohistochemical of paraffin-embedded human hepatic tissue using CSB-MA070501A0m at dilution of 1:200
 |
Immunohistochemical of paraffin-embedded human nephridial tissue using CSB-MA070501A0m at dilution of 1:200
 |
| | |
Наименование: RBP4 Monoclonal Antibody.