RCOR1 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	REST corepressor 1 (Protein CoREST), RCOR1, KIAA0071 RCOR
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q9UKL0
Иммуноген	Recombinant Human REST corepressor 1 protein (394-482AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	REST corepressor 1
Области исследований	Epigenetics and Nuclear Signaling
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA019515HD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: RCOR1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).