Объем | 100 мкл |
Синонимы | Regulator of G-protein signaling 10, RGS10, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43665 |
Иммуноген | Synthesized peptide derived from internal of human RGS10. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.<br/><br/>Hunt T.W., Nature 383:175-177(1996).<br/>Chatterjee T.K., J. Biol. Chem. 275:24013-24021(2000).<br/>Burgon P.G., J. Biol. Chem. 276:32828-32834(2001).<br/> <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using RGS10 antibody.
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