| Объем | 100 мкл |
| Синонимы | Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3), RIPK3, RIP3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y572 |
| Иммуноген | Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-120AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
| Примечание | Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cancer, Cell biology, Immunology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA897497ESR1HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA897497ESR1HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA897497ESR1HU at dilution of 1:100
 |
| | |
Наименование: RIPK3 Antibody.