RNF126 Antibody, HRP conjugatedСпецификация| Объем | 50 мкг | | Синонимы | E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126), RNF126 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9BV68 | | Иммуноген | Recombinant Human E3 ubiquitin-protein ligase RNF126 protein (39-225AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | HRP | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | E3 ubiquitin-protein ligase RNF126 | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA019828LB01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: RNF126 Antibody, HRP conjugated.
Примечание: дополнительная информация (на английском языке). |
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