Объем | 100 мкг |
Синонимы | E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43), RNF43 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q68DV7 |
Иммуноген | Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | HRP |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | E3 ubiquitin-protein ligase RNF43 |
Области исследований | Cancer, Cell biology, Immunology |
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