Объем | 100 мкл |
Синонимы | GTP-binding protein RAD, RAD, RAD1, RAS associated with diabetes, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P55042 |
Иммуноген | Synthesized peptide derived from internal of human RAD. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane By similarity. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.<br/><br/>Reynet C., Science 262:1441-1444(1993).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Moyers J.S., J. Biol. Chem. 272:11832-11839(1997).<br/> <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cardiovascular,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, HepG2 cells and MCF-7 cells, using RAD antibody.
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Immunohistochemistry analysis of paraffin-embedded human heart tissue using RAD antibody.
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Immunofluorescence analysis of A549 cells, using RAD antibody.
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