GEMIN8 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Gem-associated protein 8 (Gemin-8) (Protein FAM51A1), GEMIN8, FAM51A1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9NWZ8 | | Иммуноген | Recombinant Human Gem-associated protein 8 protein (1-242AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 | | Примечание | The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA873675LA01HU at dilution of 1:100
 | Western Blot
Positive WB detected in: HepG2 whole cell lysate, HEK293 whole cell lysate, Mouse kidney tissue
All lanes: GEMIN8 antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29 kDa
Observed band size: 29, 33 kDa
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Наименование: GEMIN8 Antibody.