| Объем | 50 мкл |
| Синонимы | selectin P ligand |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q14242 |
| Иммуноген | Fusion protein of human SELPLG |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Примечание | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cardiovascular,Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA129120(SELPLG Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA129120(SELPLG Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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Наименование: SELPLG Antibody.