SEZ6L AntibodyСпецификацияОбъем | 100 мкл | Синонимы | seizure related 6 homolog (mouse)-like | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9BYH1 | Иммуноген | Synthetic peptide of human SEZ6L | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:25-1:100 | Примечание | SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Neuroscience,Cancer | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA115417(SEZ6L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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