Объем | 100 мкл |
Синонимы | SKI-like proto-oncogene |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P12757 |
Иммуноген | Fusion protein of human SKIL |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:30-1:150 |
Примечание | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cancer |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA932063(SKIL Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
|
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA932063(SKIL Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
|
Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: Huvec cells, Primary antibody: CSB-PA932063(SKIL Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
|
| |