Объем | 100 мкл |
Синонимы | Suppression of tumorigenicity 5, HeLa tumor suppression 1, DENN domain-containing protein 2B, ST5, DENND2B |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P78524 |
Иммуноген | Synthesized peptide derived from internal of human ST5. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.<br/><br/>Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996).<br/>Amid C., Cytogenet. Cell Genet. 93:284-290(2001).<br/>Lichy J.H., Cell Growth Differ. 3:541-548(1992). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using ST5 antibody.
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