Объем | 100 мкл |
Синонимы | Acute-phase response factor |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P40763 |
Иммуноген | Peptide sequence around aa. 725~729 (P-M-S-P-R) derived from Human STAT3. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
Примечание | Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. <br/><br/>Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120.<br/>Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804.<br/>Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115.<br/>Garcia R, et al. (1998) J Biomed Sci. 5: 79-85.<br/>Bromberg J F, et al. (1999) Cell. 98: 295-303.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Developmental biology,Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela cells using STAT3(Ab-727) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3(Ab-727) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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