STAT3 Antibody, Biotin conjugatedСпецификация| Объем | 100 мкг | | Синонимы | Signal transducer and activator of transcription 3 (Acute-phase response factor), STAT3, APRF | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P40763 | | Иммуноген | Recombinant Human Signal transducer and activator of transcription 3 protein (50-240AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed:17344214). Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580). Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Signal transducer and activator of transcription 3 | | Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA022812LD01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: STAT3 Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
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