Объем | 100 мкл |
Синонимы | Transcriptional adapter 2-like, ADA2-like protein, TADA2L, KL04P, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O75478 |
Иммуноген | Synthesized peptide derived from internal of human ADA2L. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site By similarity. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.<br/><br/>Candau R., Mol. Cell. Biol. 16:593-602(1996).<br/>Ogryzko V.V., Cell 94:35-44(1998).<br/>Henriksson A., Mol. Cell. Biol. 17:3065-3073(1997). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COS-7 cells and COLO205 cells, using ADA2L antibody.
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