Объем | 100 мкл |
Синонимы | Class A helix-loop-helix transcription factor ME2, ITF-2, ITF2, Immunoglobulin transcription factor 2, MITF-2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P15884/Q99081 |
Иммуноген | Synthesized peptide derived from internal of human TCF4/12. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription By similarity. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.<br/><br/>Corneliussen B., J. Virol. 65:6084-6093(1991).<br/>Breschel T.S., Hum. Mol. Genet. 6:1855-1863(1997).<br/>Amiel J., Am. J. Hum. Genet. 80:988-993(2007).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells, using TCF4/12 antibody.
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