TFDP1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | E2F DIMERIZATION PARTNER 1, TRANSCRIPTION FACTOR DP1, TRANSCRIPTION FACTOR, SEQUENCE-SPECIFIC, DRTF1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q14186 | Иммуноген | Synthesized peptide derived from human DP-1. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.<br/><br/>K Helin, Genes & Dev., Oct 1993, 7: 1850 - 1861.<br/>B Shan, Cell Growth Differ., Jun 1996, 7: 689.<br/>Hironori Ishida, J. Biol. Chem., Jul 2005, 280: 24642 - 24648.<br/>Wing Y. Chang, J. Biol. Chem., Dec 2004, 279: 51343 - 51353.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, using DP-1 antibody.
| Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using DP-1 antibody.
| Immunofluorescence analysis of HeLa cells, treated with Forskolin (40nM, 30mins), using DP-1 antibody.
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