| Объем | 50 мкг |
| Синонимы | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)], TFRC |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P02786 |
| Иммуноген | Recombinant Human Transferrin receptor protein 1 protein (94-754AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Cancer, Cardiovascular, Immunology, Metabolism, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Transferrin receptor protein 1 antibody at 2µg/ml
Lane 1: U251 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 85 kDa
Observed band size: 85 kDa
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Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA07219A0Rb at dilution of 1:100
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Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: TFRC antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 85 kDa
Observed band size: 85 kDa
 |
Immunocytochemistry analysis of human colon cancer using CSB-PA07219A0Rb at dilution of 1:100
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Immunofluorescent analysis of HepG2 cells using CSB-PA07219A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: TFRC Antibody.