Timp1 AntibodyСпецификация| Объем | 100 мкг | | Синонимы | Metalloproteinase inhibitor 1 (Tissue inhibitor of metalloproteinases 1) (TIMP-1), Timp1, Timp-1 | | Клональность | Polyclonal Antibody | | Организм | Rat | | uniprot | P30120 | | Иммуноген | Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA) | | Источник | Rabbit | | Видовая специфичность | Rat | | Применение | ELISA | | Примечание | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells, procathepsin L is required for maximal activity. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Cancer, Cardiovascular, Cell biology, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | | | |
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Наименование: Timp1 Antibody.