Объем | 50 мкл |
Синонимы | toll-like receptor 3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O15455 |
Иммуноген | Fusion protein of human TLR3 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Immunology,Microbiology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA697913(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA697913(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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