| Объем | 100 мкл |
| Синонимы | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase, UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase, Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y223 |
| Иммуноген | Synthesized peptide derived from C-terminal of human GNE. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.<br/><br/>Lucka L., FEBS Lett. 454:341-344(1999).<br/>Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).<br/>Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cardiovascular,Developmental biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from NIH/3T3 cells, using GNE antibody.
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Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using GNE antibody.
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Наименование: GNE Antibody.