TP53INP2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | p53-inducible protein U, PIG-U, PINH, T53I2, tumor protein p53 inducible nuclear protein 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q8CFU8 | Иммуноген | Synthesized peptide derived from internal of human TP53INP2. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.<br/><br/>Baumgartner B.G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.<br/>Deloukas P., Nature 414:865-871(2001).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Cell biology | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 antibody.
| Immunofluorescence analysis of MCF-7 cells, using TP53INP2 antibody.
| | |
Информация для заказа |