TP63 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | tumor protein p63 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9H3D4 | | Иммуноген | Fusion protein of human TP63 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 | | Примечание | This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA158988(TP63 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA158988(TP63 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 | Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse bladder tissue, Primary antibody: CSB-PA158988(TP63 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Наименование: TP63 Antibody.