| Объем | 50 мкг |
| Синонимы | Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2), TRPM2, EREG1 KNP3 LTRPC2 TRPC7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O94759 |
| Иммуноген | Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (60-119AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Cell biology, Metabolism, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: TRPM2 antibody at 3µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Mouse brain tissue
Lane 3: A549 whole cell lysate
Lane 4: K562 whole cell lysate
Lane 5: Mouse kidney tissue
Lane 6: Human placenta tissue
Lane 7: Mouse spleen tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 172, 166, 96 kDa
Observed band size: 70, 180 kDa
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA007779LA01HU at dilution of 1:100
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Immunofluorescent analysis of HepG2 cells using CSB-PA007779LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Immunohistochemistry analysis of human melanoma using CSB-PA007779LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA007779LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Immunofluorescent analysis of A549 cells using CSB-PA007779LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: TRPM2 Antibody.