TSC2 AntibodyСпецификация| Объем | 100 мкг | | Синонимы | Tuberin (Tuberous sclerosis 2 protein), TSC2, TSC4 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P49815 | | Иммуноген | Recombinant Human Tuberin protein (1396-1496AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IF, Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200 | | Примечание | In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Tuberin | | Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cell biology, Metabolism, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western Blot
Positive WB detected in: Mouse lung tissue
All lanes: TSC2 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 201, 196, 199, 194, 190, 188, 26 kDa
Observed band size: 201 kDa
 | Immunofluorescent analysis of Hela cells using CSB-PA343033LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: TSC2 Antibody.