GRM8 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | GPRC1H, MGLUR8, mGlu8, GLUTAMATE RECEPTOR, METABOTROPIC | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O00222 | Иммуноген | Synthesized peptide derived from human GluR8. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<br/><br/>Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.<br/>RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.<br/>Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.<br/>V. Bruno, J. Neurosci., Sep 2000, 20: 6413.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Neuroscience | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR8 antibody.
 | Western blot analysis of extracts from mouse brain, using GluR8 antibody.
 | Western blot analysis of extracts from k562 cells (Lane 2), using mGluR8 antiobdy. The lane on the left is treated with synthesized peptide.
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