Объем | 100 мкл |
Синонимы | Transcription cofactor HES-6, Hairy and enhancer of split 6, C-HAIRY1, HES6, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q96HZ4 |
Иммуноген | Synthesized peptide derived from N-terminal of human HES6. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6<br/><br/>Bae S.-K., Development 127:2933-2943(2000).<br/>Vasiliauskas D., Mech. Dev. 98:133-137(2000).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, using HES6 antibody.
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