Объем | 50 мкл |
Синонимы | IKAROS family zinc finger 3 (Aiolos) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UKT9 |
Иммуноген | Fusion protein of human IKZF3 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA577111(IKZF3 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA577111(IKZF3 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
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