| Объем | 100 мкл |
| Синонимы | IRF2, Interferon regulatory factor 2, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P14316 |
| Иммуноген | Synthesized peptide derived from internal of human IRF2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.<br/><br/>Itoh S., Nucleic Acids Res. 17:8372-8372(1989).<br/>Cha Y., J. Biol. Chem. 269:5279-5287(1994).<br/>Staal A., J. Cell. Physiol. 185:269-279(2000).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells and COLO205 cells, using IRF2 antibody.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using IRF2 antibody.
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Наименование: IRF2 Antibody.