Объем | 50 мкл |
Синонимы | vacuolar protein sorting 33 homolog B (yeast) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9H267 |
Иммуноген | Fusion protein of human VPS33B |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,ELISA:1:2000-1:10000, IHC:1:30-1:150 |
Примечание | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA947382(VPS33B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA947382(VPS33B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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