| Объем | 100 мкг |
| Синонимы | DNA-dependent metalloprotease WSS1 (EC 3.4.24.-) (DNA damage response protein WSS1) (SUMO-dependent isopeptidase WSS1) (Weak suppressor of SMT3 protein 1), WSS1 |
| Клональность | Polyclonal Antibody |
| Организм | Saccharomyces cerevisiae |
| uniprot | P38838 |
| Иммуноген | Recombinant Saccharomyces cerevisiae DNA-dependent metalloprotease WSS1 protein (1-269AA) |
| Источник | Rabbit |
| Видовая специфичность | Saccharomyces cerevisiae |
| Применение | ELISA |
| Примечание | Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped TOP1 from chromatin. DPC proteolysis enables the repair of the lesions via downstream DNA repair pathways. May be recruited to DPCs via the SUMOylation of substrate proteins at damaged DNA sites. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | DNA-dependent metalloprotease WSS1 |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
| | |
Наименование: WSS1 Antibody, Biotin conjugated.