Объем | 100 мкл |
Синонимы | dkfzp451j1719, duba8, otu1, otud2, pro0907 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q5VVQ6 |
Иммуноген | Synthesized peptide derived from internal of human YOD1. |
Источник | Rabbit |
Видовая специфичность | Human, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Gregory S.G., Nature 441:315-321(2006).<br/>Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO cells, using YOD1 antibody.
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