Объем | 100 мкг |
Синонимы | Zinc finger protein 57 homolog (Zfp-57) (Zinc finger protein 698), ZFP57, C6orf40 ZNF698 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9NU63 |
Иммуноген | Recombinant Human Zinc finger protein 57 homolog protein (183-295AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
Примечание | Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Zinc finger protein 57 homolog |
Области исследований | Epigenetics and Nuclear Signaling, Developmental biology, Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: HepG2 whole cell lysate, 293 whole cell lysate, Mouse brain tissue
All lanes: ZFP57 antibody at 13.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 52, 60, 62 kDa
Observed band size: 52 kDa
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