| Объем | 100 мкл |
| Синонимы | MLL partner containing FYVE domain, MPFYVE, ZFY19, Zinc finger FYVE domain-containing protein 19, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96K21 |
| Иммуноген | Synthesized peptide derived from internal of human ZFYVE19. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.<br/><br/>Chinwalla V., Oncogene 22:1400-1410(2003).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells, using ZFYVE19 antibody.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ZFYVE19 antibody.
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Наименование: ZFYVE19 Antibody.