| Объем | 100 мкл |
| Синонимы | CD104 antigen, GP150, ITB4, integrin beta-4, integrin beta-4C |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P16144 |
| Иммуноген | Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.<br/><br/>Suzuki S., EMBO J. 9:757-763(1990).<br/>Hogervorst F., EMBO J. 9:765-770(1990).<br/>Tamura R.N., J. Cell Biol. 111:1593-1604(1990).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using ITGB4 (Ab-1510) antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ITGB4 (Ab-1510) antibody.
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Наименование: ITGB4 (Ab-1510) Antibody.