| Объем | 50 мкг |
| Синонимы | Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme), KLK6, PRSS18 PRSS9 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q92876 |
| Иммуноген | Recombinant Human Kallikrein-6 protein (22-244AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Neuroscience, Cancer, Cell biology, Tags & Cell Markers, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: KLK6 antibody at 5µg/ml
Lane 1: Mouse liver tissue
Lane 2: Mouse brain tissue
Lane 3: A375 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 27, 16, 5 kDa
Observed band size: 27 kDa
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA842165LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA842165LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA842165LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: KLK6 Antibody.