Объем | 50 мкг |
Синонимы | Major capsid protein L1, L1 |
Клональность | Polyclonal Antibody |
Организм | Human papillomavirus type 18 |
uniprot | P06794 |
Иммуноген | Recombinant HPV18 Major capsid protein L1 protein (1-568AA) |
Источник | Rabbit |
Видовая специфичность | Human papillomavirus type 18 |
Применение | ELISA, WB, Recommended dilution: WB:1:1000-1:5000 |
Примечание | Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Major capsid protein L1 |
Области исследований | Cancer, Microbiology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Major capsid protein L1 antibody at 2µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 62 kDa
Observed band size: 62 kDa
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